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REFLECTIONS

                                                                                                              Dyslipidaemia
     Dyslipidaemia Global Newsletter #6 2023



                  TABLE OF CONTENTS

            KEY ARTICLES

          EPIDEMIOLOGY                                          Welcome to our next installment of Reflections Dyslipidaemia
          Global effect of modifiable risk factors on cardiovascular   Global Newsletter, where an international Scientific Planning
          disease and mortality. Global Cardiovascular Risk Consortium.   Committee summarizes and provides expert commentary
          N Engl J Med. 2023 Oct 5;389(14):1273-1285.           on the latest clinical and real-world evidence in the field of
                                                                                                              Dyslipida
        CLINICAL GUIDELINES/STATEMENTS                          dyslipidaemia. These articles are chosen based on their
          2023 ESC Guidelines for the management of acute       significance to every day clinical practice. As with the previous
          coronary syndromes. Byrne RA, et al. Eur Heart J. 2023 Oct   newsletters, we invite you to interact through links to short
          12;44(38):3720-3826.                                  video commentaries from our SPC, links to videos, along with
           Women, lipids, and atherosclerotic cardiovascular disease:   hyperlinks to full articles for in-depth study and reflection. A
          A call to action from the European Atherosclerosis Society.   new feature in this newsletter is our Conference Corner, where
          Roeters van Lennep J, et al. Eur Heart J. 2023 Oct 14;44(39):4157-  we highlight some abstracts of interest from the recent 2023
          4173.                                                 ESC Conference in Amsterdam.
        TREATMENT
                                                                Prof. Farnier (Chair)
          Statin discontinuation after coronary revascularization.
          Yamamoto K, et al. Am J Cardiol. 2023 Oct 3:S0002-
          9149(23)01029-9.                                      SCIENTIFIC PLANNING COMMITTEE
         SPECIAL POPULATIONS
          Aggressive LDL-C lowering and the brain: Impact on           Prof. Michel Farnier        Prof. Augusto Lavalle
          risk for dementia and hemorrhagic stroke: A scientific       (France)                    Cobo
          statement from the American Heart Association.                                           (Argentina)
          Goldstein LB, et al. Arterioscler Thromb Vasc Biol. 2023
          Oct;43(10):e404-e442.
           Pitavastatin to prevent cardiovascular disease in HIV       Prof. Miriam Sandin         Prof. Lourdes Santos
          infection. Grinspoon SK, et al. N Engl J Med. 2023 Aug       (Spain)                     (Philippines)
          24;389(8):687-699.
        CONFERENCE CORNER

           Highlighted abstracts of interest from the ESC 2023         Prof. Ahmed Shawky          Prof. Marcin Welnicki
          Conference.                                                  (Egypt)                     (Poland)

             ADDITIONAL ARTICLES OF INTEREST


    EPIDEMIOLOGY


     Global effect of modifiable risk factors on cardiovascular disease and mortality.
     Global Cardiovascular Risk Consortium. N Engl J Med. 2023 Oct 5;389(14):1273-1285.


     Modifiable risk factors such as body mass index
     (BMI), systolic blood pressure (SBP), non-high-density
     lipoprotein (non-HDL), cholesterol level, current tobacco
     smoking, and diabetes, are thought to increase the risk of
     cardiovascular disease and death.

     This pooled analysis harmonized individual-level data
     from 112 cohort studies conducted in 34 countries and
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